Xin Wang : Associate Professor
Department of Chemical Biology, School of Pharmaceutical Sciences
Phone: 010-82801504
Fax: 010-82716956
Email: xinwang@bjmu.edu.cn
Teaching Courses: Fundamental Organic Chemistry
Research Interests: Design, synthesis and biological study of heterocyclic compounds; New methods of organic synthesis. More than 20 papers have been published and three Chinese invention patents were applied.
Honor and Awards
1) first-class awards of teaching competition(school of pharmaceutical sciences, 2003, 2007)
2) third-class awards of teaching competition (Peking university, 2004, 2007)
3) second-class Scientific and Technical Advance Awards of Beijing(2005)
Representative Publications
1) Xin Wang, Yaowu Sha, Zemei Ge, Wei Wang, Runtao Li*. Fragmentation patterns of novel dithiocarbamate derivatives with pharmaceutical activity under electrospray ionization tandem mass spectrometry conditions. Rapid commun. mass spectrum., 2011, 25(2): 349-354.
2) Xin Wang, Ang Li, Wei Wang, Runtao Li*. Fragmentation patterns of novel dispirocyclopiperazinium dibromides with strong analgesic activity under electrospray ionization tandem mass spectrometry conditions. Journal of Chinese pharmaceutical sciences, 2011, 20(1): 42-46.
3) Jin-ming Liu, Xin Wang, Ze-mei Ge, Qi Sun, Tie-ming Cheng, Run-tao Li *. Solvent-free organocatalytic Michael addition of diethyl malonate to nitroalkenes: the practical synthesis of Pregabalin and g-nitrobutyric acid derivatives. Tetrahedron 2011, 67 (3): 636-640.
4) Xin Wang, Wen-Jun Liu, Gang Li, Jia Ye, Tie-ming Cheng, Run-tao Li. Synthesis and Analgesic Activity of Dispirocyclopiperazinium Analogues. Chin. J. Org. Chem., 2010, 30(10): 1559-1562.
5) Junfeng Wang, Xin Wang, Zemei Ge,* Tieming Cheng and Runtao Li.* Highly enantioselective Michael addition of cyclopentanone with chalcones via novel di-iminium mechanism. Chem. Commun., 2010, 46: 1751-1753.
6) Xin Ai, Xin Wang*, Jin-ming Liu, Ze-mei Ge, Tie-ming Cheng, Run-tao Li* An effective Aza-Michael addition of aromatic amines to electron-deficient alkenes in alkaline Al2O3. Tetrahedron, 2010, 66 (29): 5373-5377.
7) Shuai Xia, Xin Wang,* Ze-mei Ge, Tie-ming Cheng, Run-tao Li* An Efficient Synthesis of aryldithiocarbamic acid esters from Michael addition of electron-deficient alkenes with arylamines and CS2 in solid media alkaline Al2O3 Tetrahedron, 2009, 65 (5): 1005-1009
8) Ang Li, Xin Wang, Cai-Qin Yue, Jia Ye, Chang-Ling Li and Run-Tao Li* Unique spirocyclopiperazinium salt. Part 4: Modification of dispirocyclopiperazinium (DSPZ) salts as analgesics，Bioorg. Med. Chem. Lett., 2007, 17: 5078–5081;
9) Xin Wang, Yaowu Sha, Xueling Hou, Runtao Li. Electrospray ionization tandem mass spectrometric analysis of fragmentation patterns of dithiocarbamate derivatives. Rapid commun. mass spectrum., 2006; 20: 719-722.
10) Xin Wang, Yaowu Sha, Runtao Li. Fragmentation patterns of novel dispirocyclopiperazinium dibromides with strong analgesic activity under electrospray ionization tandem mass spectrometry conditions. Rapid commun. mass spectrum., 2004; 18: 829-833.
11) Xin Wang, Yaowu Sha, Runtao Li. Fragmentation patterns of novel dispirocyclopiperazinium dibromides with strong analgesic activity under electrospray ionization tandem mass spectrometry conditions. Int. J Mass Spectrom., 2004; 235: 111–115.
12) Xin Wang, Feng-Li Gao, Hong-Bin Piao, Tie-Ming Cheng, Run-Tao Li. Unique spirocyclo- piperazinium salt. Part 2: Synthesis and structure-activity relationship of dispirocyclo- piperazinium salts as analgesics. Bioorg. Med. Chem. Lett., 2003, 13:1729-1732.
13) Feng-Li Gao, Xin Wang, Hong-Mei Zhang, Tie-Ming Cheng, Run-Tao Li. Unique spirocyclo- piperazinium salt I: Synthesis and structure-activity relationship of spirocyclopiperazinium salts as analgesics. Bioorg. Med. Chem. Lett., 2003, 13: 1535-1537.
14) Jing-Chao Dong, Xin Wang, Run-Tao Li, Hong-Mei Zhang, Tie-Ming Cheng, and Chang-Ling Li. Synthesis and analgesic activity of hydrochlorides and quaternary ammoniums of epibatidine incorporated with amino acid ester. Bioorg. Med. Chem. Lett., 2003, 13: 4327-4329.
