代表论文

     2015

1. Zhang, Yu; Liu, Bin; Wu, Xingyu; Li, Ridong; Ning, Xianling; Liu, Yu; Liu, Zhenming; Ge, Zemei; Li, Runtao;*Yin, Yuxin*. New pyridin-3-ylmethyl carbamodithioic esters activate pyruvate kinase M2 and potential anticancer lead compounds,Bioor. Med. Chem, 2015, 23(15), 4815-4823. IF=2.793
2. Liu, Bin; Huang, Xuhu; Wang, Xin; Ge, Zemei*; Li, Runtao*.Palladium catalyzed amide-oxazoline directed C-H acetoxylation of arenes. Org. Chem. Front.2015, 2(7), 797-800
3. Wang, Jie; Tan, Hailiang; Sun, Qi; Ge, Zemei; Wang, Xin; Wang, Yinye*; Li, Runtao*.Design, synthesis and biological evaluation of pyridazino[3,4,5-de]-quinazolin-3(2H)-one as a new class of PARP-1 inhibitors. Bioor. Med. Chem Letters, 2015, 25(11),2340-2344.IF=2.42
4. Bai, Zhushuang; Ji, Ling; Ge, Zemei; Wang, Xin*; Li, Runtao*.Asymmetric Michael addition reactions of nitroalkanes to 2-furanones catalyzed by bifunctional thiourea catalysts.Org. Biomol. Chem.2015, 13(19), 5363-5366.IF=3.562
5. Huang, Xuhu; Wang, Shucheng; Li, Bowen; Wang, Xin; Ge, Zemei*; Li, Runtao*.Iodine-triphenylphosphine mediated sulfenylation of imidazoheter-ocycles with sodium sulfonates,RSC Advances, 2015, 5(29), 22654-22657. IF=3.84
6. Wang, Shucheng; Huang, Xuhu; Li, Bowen; Ge, Zemei; Wang, Xin; Li, Runtao*. A metal-free synthesis of oxindoles by a radical addition-cyclization onto N-arylacrylamides with xanthates.Tetrahedron, 2015, 71(12), 1869-1875. IF=2.641
7. Wang, Huiling; Li, Ridong; Li, Li; Ge, Zemei; Zhou, Rouli*; Li, Runtao*.LRD-22, a novel dual dithiocarbamatic acid ester, inhibits Aurora-A kinase and induces apoptosis and cell cycle arrest in HepG2 cells.Biochem. Biophys. Res. Commun.2015, 458(1), 201-207. IF=2.297
8. Li, Ri-Dong; Wang, Hui-Ling; Li, Ying-Bo; Wang, Zhong-Qing; Wang, Xin; Wang, Yi-Tao; Ge, Ze-Mei*; Li, Run-Tao*.Discovery and optimization of novel dual dithiocarbamates as potent anticancer agents.Eur. J. Med. Chem.2015, 93, 381-391. IF=3.447
9. Luo, Laichun; Meng, Lanlan; Peng, Yangqiu; Xing, Yongning; Sun, Qi*; Ge, Zemei; Li, Runtao*.ZnCl₂-Promoted One-Pot Three-Component Synthesis of MultisubstitutedThiazolo[4,5-b]pyridines and Thieno[2,3- b:4,5-b']dipyridines.Eur. J. Org. Chem.2015, 2015(3), 631-637. IF=3.065
10. Zhao, Shuo; Wu, You; Sun, Qi*; Cheng, Tie-Ming; Li, Run-Tao*. Triphenylphos-phine-N- Bromosuccinimide Mediated ChemoselectiveCyclodehydration of Diols.Synthesis,2015, 47(8), 1154-1162,IF=2.689
11. Shucheng Wang, Xuhu Huang, Yanzhao Wen, Zemei Ge, Xin Wang, Runtao Li*. Cascade synthesis of spirooxindole d-lactone derivatives through N-aryl hydroxymethylacrylamides with xanthates.Tetrahedron, 2015, 71, 8117-8122,IF=2.641
12. Su, XiangbaoMeng. Synthesis and Biological Evaluation of Thiabendazole Derivatives as Anti-angiogenesis and vascular disrupting Agents, Bioorg. Med. Chem., 2015，23，3774-3780. IF=2.951
13. ShuaiMeng, Tian Tian, Dong Han, Lin-Na Wang, Shao-Geng Tang, Xiang-BaoMeng, Zhong-Jun Li, Efficient Assembly of oligomannosides using the hydrophobically assisted switching phase method, Org. Biomol. Chem.,2015, 13, 6711-6722. IF=3.562
14. Yunfeng Li, Meng Yao, Zhongjun Li, XiangbaoMeng, Stereoselective and regioselective one-pot synthesis of polyhydroxy bicyclic diazenes and hydrazones from methyl 6-deoxy-6-iodohexosides, Tetrahedron, 2015, 71, 5385-5390.IF=2.641
15. XiaochaoXue, Wei Li, Zhaojun Yin, XiangbaoMeng, Zhongjun Li, Concise and direct construction of cis-pyrano[4,3-b]pyran-5-one skeleton from glucal derivatives: synthesis of ent-4-deoxy-2,3-di-epi-dinemasone BC, Tetrahedron Lett., 2015, 56, 5228-5230. IF=2.391
16. Pengzhan Qian, Wang Yao, Lubai Huang, XiangbaoMeng, Zhongjun Li, A mild and efficient method for the selective cleavage of primary p-methoxybenzyl protecting group of saccharides by Co₂(CO)₈-Me₂PhSiH-CO system, Tetrahedron Lett., 2015, 56, 5238-5241. IF=2.391
17. Shan Jiang, Shan Niu, Zhi-Hui Zhao, Zhong-Jun Li, Qing Li, Synthesis of a series of novel heteroglycoclusters and homoglycoclusters and the study of their anti-adhesion activities, Carbohydr. Res., 2015, 414, 39-45. IF=1.996
18. Chao Zhang, Shasha Li, Liyan Ji, Shan Liu, Zhongjun Li, Shuchun Li, and XiangbaoMeng, synthesis and antitumor activity of non-camptothecin topoisomerase I inhibitors, Bioorg. Med. Chem. Lett.,2015, 25, 4693-4696. IF=2.331
19. Yuanyuan Cao, Yu Zhang, Shaotong Wu, Quanzhi Yang, Xuefeng Sun, Jianxiong  Zhao, Fen Pei, Ying Guo, Chao Tian, Zhili Zhang, Haining Wang, Liying Ma, Junyi Liu,* and Xiaowei Wang*.  Synthesis and biological evaluation of pyridinone analogues as novel potent HIV-1 NNRTIs. Bioorg. Med. Chem.23 (2015) 149–159
20. Yu Zhang, Xuefeng Sun,Ningning Fan,Jianxiong Zhao,Jing Tu,Xiangmei Chen,Junyi Liu* and Xiaowei Wang*. 5-Iodo-2-arylalkylthio-6-aryl pyrimidin-4(3H)-ones as non-nucleoside anti-HBV agents. Med. Chem. Commun., 2015, 6, 1438–1443
21. Tong-Bo Zhang,Yuan-Yuan Cao, Shao-Tong Wu, Yu Zhang, Ying Guo,Jian-Xiong Zhao, Xue-Feng Sun,Quan-Zhi Yang,Zhi-Li Zhang, Chao Tian, Jun-Yi Liu^]*and Xiao-Wei Wang.^*An approach to synthesis of pyrimido[b]azepines via Ruthenium-catalyzed ring-closing metathesis. Synthesis 2015, 47, 3292–3300
22. Weisi Xu,Jianxiong Zhao, Jianping Sun, Qianqian Yin,Yan Wang, Yang Jiao, Junyi Liu, ShiboJiang, Yiming Shao, Xiaowei Wang,* and Liying Ma.* The HEPT analogue, 1-((benzyloxy) methyl)-6-(3, 5-dimethylbenzyl)-5- iodopyrimidine-2, 4(1H, 3H)-dione (WPR-6), is active against a broad spectrum of HIV-1 strains of different subtypes with drug-resistance. Antimicrob. Agents Chemother.  2015, 59:84882-4888
23. Xianling Ning, Mengmeng Yuan, Ying Guo, Chao Tian, Xiaowei Wang, Zhili Zhang & Junyi Liu*. Neuroprotective effects of (E)-3,4-diacetoxystyryl sulfone and sulfoxide derivatives in vitro models of Parkinson's disease.J Enzyme Inhib Med Chem,2015, 1475-6366
24.  Ying-Yuan Lu, Xin Wang, Xiao-WeiWang, Jun-Yi Liu, Pu Li, Hong Ren, Ya-Qing Lou, Chuang Lu and Guo-Liang Zhang. Development and validation of a high performance liquid chromatography method for determination of 6-benzyl-1-benzyloxymethyl-5-iodouracil (W-1), a novel non-nucleoside reverse transcriptase inhibitor and its application to a pharmacokinetic study in rats. Biomed. Chromatogr.2015，DOI 10.1002/bmc.3457
25. Shaotong Wu,？ Qianqian Yin,？ Liang Zhao, Ningning Fan, Xiaowan Tang, Jianxiong Zhao, Tao Sheng, Ying Guo, Chao Tian, Zhili Zhang, Weisi Xu, Zhenming Liu, Shibo Jiang, Liying Ma,* Junyi Liu* and Xiaowei Wang*, A stereo configuration-activity study of 3-iodo-4-(2-methylcyclohexyloxy)-6-phenethylpyridin-2 (2H)-ones as potency inhibitors of HIV-1 variants. Org. Biomol. Chem.2015,  DOI: 10.1039/c5ob02154e
26. Chao Tian, Zhili Zhang, Shouxin Zhou, Mengmeng Yuan, Xiaowei Wang, Junyi Liu？, Synthesis, Antifolate and Anticancer Activities of N5-Substituted 8,10-Dideazatetrahydrofolate Analogues. Chemical Biology & Drug Design,2015, doi: 10.1111/cbdd.12681
27. Xiao-Gai Yang*, Kui Wang, Focusing on the link between diabetes, Alzheimer's disease and cancer for the discovery of new medicines, Curr Top Med Chem, 2016,.16(7):675-676
28. Min Feng, Yun-Zhou Fan, Xiao-Jie Ma, Jin-Xia Li, Xiao-Gai Yang*, The gadolinium-based contrast agent Omniscan？ promotes in vitro fibroblast survival through in situ precipitation, Metallomics, 2015, 7:1103-1110
29. Zhang, Q.; Jiang, Y.; Gou, B.-D.; Huang, J.; Gao, Y.-X.; Zhao, J.-T.; Zheng, L.; Zhao, Y.-D.;      Zhang, T.-L.; Wang, K., In situ detection of calcium phosphate clusters in solution and wet   amorphous phase by synchrotron X-ray absorption near-edge spectroscopy at calcium K-edge.   Cryst. Growth Des.2015,15(5), 2204-2210.
30.  Wang N, Wang Z, Niu X, Yang X, Synthesis, characterization and anti-diabetic therapeutic potential of novel aminophenol-derivatized nitrilotriacetic acid vanadyl complexes, J. Inorg. Biochem., 2015, 152: 104–113
31.  Wang X, Lei R, Huang H, Wang N, Yuan L, Xiao R, Bai L, Li X, Li L, Yang, X，The permeability and transport mechanism of graphene quantum dots (GQDs) across the biological barrier, Nanoscale, 2015, 7: 2034 - 2041
32. Peng Xu, Min Li, Yanping Βai, Wei Lu, Xiaomei Ling,*,Weidong Li,*，The effects of piracetam on heroin-induced CPP and neuronal apoptosis in rats，Drug and Alcohol Dependence, 2015.150: 141-146 （SCI 3.423）
33. Zhongjie Li, Yiran Zhao, Weiwei Lin, Xiaobo Hu, MinYe*, Xiaodan Zhang, Xiaomei Ling*，Rapid screening and identification of active ingredients in licoriceextract interacting with V3 loop region of HIV-1 gp120 using ACE andCE-MS，Journal of Pharmaceutical and  Biomedical Analysis, Journal of Pharmaceutical and Biomedical Analysis 111 (2015) 28–35 (SCI:2.979)
34. Jing Li^, Wensi Lin, Weiwei Lin, Peng Xu, Jianmei Zhang, Haisong Yang,Xiaomei Ling^？, Metabolic profiling study on potential toxicity and immunotoxicity-biomarker discovery in rats treated with cyclophosphamide using HPLC-ESI-IT-TOF-MS, Biomedical Chromatography，2015, 29(5):768–776 (SCI:1.942)