Jian Huang: Ph. D,Associate Professor
Tel: +86-10-82801539
E-mail: hj_by2005@yahoo.com.cn
Address: Department of Chemical Biology, School of Pharmaceutical Sciences,Peking University, Beijing 100191, China
Education:
l Ph.D. in Pharmaceutical Chemistry,
l MS in Bioinorganic Chemistry,
l BS in Analytical Chemistry,
Professional Background
l 2009~ present, Associate Professor, Department of Chemical Biology,
l 2005~ present, Lecture, Department of Chemical Biology,
l 1998~ 2002, Lecture, Department of Chemical Biology,
Teaching:
Inorganic Chemistry,Chemical Biology II-Advanced Biological Inorganic Chemistry
Research Interest
l Comparative study of calcium phosphate microparticles formation from biological medium with artificial synthetic nanohydroxyapatite and their in vitro effects on osteogenic differentiation
l Effects of lanthanides or flavonoids on the pathological process of osteoporosis.
l Mimic of biomineralization process
Representative Publications
1. Jian huang, Xi. Wang, Tian-lan Zhang, Kui Wang. Alterations of ovariectomized rat bone and impact of non-collagenous proteins on mineralization. Joint Bone Spine, 2009, 76(2):176-183
2. Shi Yanling, Wang Liwen, Huang Jian, Gou Baodi, Zhang Tianlan, Wang Kui. Lanthanum Suppresses Osteoblastic Differentiation Via Pertussis Toxin-Sensitive G Protein Signaling in Rat Vascular Smooth Muscle Cells. Journal of Cellular Biochemistry 2009, 108: 1184-1191
3. Wang Chen-Guang, Liao Jia-Wang, Gou Bao-Di, Huang Jian, Tang Rui-Kang, Tao Jin-Hui, Zhang Tian-Lan, Wang Kui. Crystallization at Multiple Sites inside Particles of Amorphous Calcium Phosphate.
4. Xi Wang, Jian Huang*, Tianlan Zhang , Kui Wang. Cytoskeleton reorganization and FAK phosphorylation are involved in lanthanum (III)-promoted proliferation and differentiation in rat osteoblasts. Progress in Nature Science 2009,19: 331-335
5. Xi Wang, Lan Yuan, Jian Huang*, Tian-Lan Zhang*, Kui Wang. Lanthanum Enhances in vitro Osteoblast Differentiation via Pertussis Toxin-sensitive Gi Protein and ERK Signaling Pathway. Journal of Cellular Biochemistry 2008, 105: 1307-1315
6. Jian huang, Lan Yuan, Xi. Wang, Tian-lan Zhang, Kui Wang. Icarin and its glycosides enhance osteoblastic ,but suppress osteoclastic, differentiation and activity in vitro. Life Sciences, 2007,81(10):832-840 Jian Huang, Jina-Chao Zhang, Tian-Lan Zhang, Kui Wang. Icariin suppresses bone resorption activity of rabbit osteoclasts in vitro. Chinese Science Bulletin, 2007, 52(7):890-895. ‘
7. Jian Huang, Tian-Lan Zhang, Shan-jin Xu, Kui Wang, Jing Zhang, Ya-Ning Xie.. Effects of Lanthanum on Composition, Crystal Size and Lattice Structure of Femur Bone Mineral of Wistar Rats. Calcif Tissue Int, 2006, 78(4):241–247