成波
电话:(010)-82805108(办公室)
E-mail: pkuchengbo@pku.edu.cn
通讯地址:北京市海淀区学院路38号北京大学医学部药学楼633
个人简历:
2022-09 至 今, 北京大学, 药学院化学生物学系, 助理研究员(董甦伟研究员课题组)
2016-07 至2022-06, 北京大学, 化学院化学生物学, 博士后(陈兴教授课题组)
2011-09 至2016-06, 北京大学, 化学院化学生物学, 博士
2007-09 至2011-06, 华中农业大学, 理学院化学系, 学士
主要从事专业为化学糖生物学,研究方向为非天然糖设计合成、聚糖标记与分析、聚糖结合蛋白鉴定、基于糖肽和糖脂的ABPP研究。作为主持人获国家自然科学基金青年基金、“北京大学博雅博士后”和“北京分子科学国家研究中心BMS Junior Fellowship”和北京大学李革赵宁生命科学青年研究基金等资助。
1. Cheng, Bo#,*; Wang, Chunting#; Hao,Yi#, Wang, Jiankun; Xia, Xiaoqian; Zhang, Hao; He, Rundong; Zhang, Shaoran; Dai, Peng; Chen, Xing *. Facile Synthesis of Clickable Unnatural Sugars in the Unprotected and 1,6-Di-O-Acylated Forms for Metabolic Glycan Labeling. Chemistry-a European Journal 2023, 29, e202203054
2. Cheng, Bo*; Wan, Yi; Tang, Qi; Du, Yifei; Xu, Feiyang; Huang, Zhimin; Qin, Wei; Chen Xing. A Photocaged Azidosugar for Light-Controlled Metabolic Labeling of Cell-Surface Sialoglycans. Chin. J. Chem. 2022, 40, 806-812
3. Cheng, Bo; Tang, Qi; Zhang, Che; Chen, Xing*. Glycan Labeling and Analysis in Cells and in Vivo. Annu. Rev. Anal. Chem. 2021, 14, 363-387
4. Cheng, Bo; Chen, Xing*. Chemical Labeling and Analysis of Sialoglycans. Chin. Sci. Bull. 2020, 65 (27), 2985-2997
5. Cheng, Bo; Dong, Lu; Zhu, Yuntao; Huang, Rongbing; Sun, Yuting; You, Qiancheng; Song, Qitao; Paton, James C.; Paton, Adrienne W.; Chen, Xing *. 9-Azido Analogues of Three Sialic Acid Forms for Metabolic Remodeling of Cell-Surface Sialoglycans. ACS Chem. Biol. 2019, 14, 2141-2147
6. Cheng, Bo; Xie, Ran; Dong, Lu; Chen, Xing. Metabolic Remodeling of Cell-Surface Sialic Acids: Principles, Applications, and Recent Advances. ChemBioChem 2016, 17, 11-27
7. Wang, Jie #; Cheng, Bo#; Li, Jie#; Zhang, Zhaoyue; Hong, Weiyao; Chen, Xing*; Chen, Peng R*. Chemical Remodeling of Cell-Surface Sialic Acids through A Palladium-Triggered Bioorthogonal Elimination Reaction. Angew. Chem. Int. Ed. 2015, 54, 5364-5368