张天蓝： 博士，教授，博士生导师
电话：(010)-8280 1539 (办公室)
E-mail: tlzhang@bjmu.edu.cn
通讯地址：北京市海淀区学院路38号，北京大学医学部药学院化学生物学系
邮编：100191
1978年10月至1982年7月就读于华南工学院化学系，获化学专业理学学士学位。1984年9月至1987年7月就读于郑州大学/河南化学研究所，获无机化学专业理学硕士学位，此后在河南化学研究所从事配合物光化学和激发态电化学研究。1994年9月至1995年9月在英国帝国理工学院光分子科学中心(Centre for Photomolecular Sciences, Imperial College, London)学习光生物化学。1995年任河南化学研究所副研究员。1996年9月至1999年7月就读于北京医科大学，获药物化学专业理学博士学位并留校任教。2000年转为副教授，2004年至今为教授；其间，2005年6月至2008年1月曾任首都医科大学教授。
教学：
讲授本科生课程无机化学和研究生课程固态生物无机化学。
科研：
主要研究方向是抗白血病药物和生物矿化。
代表性论文：
1. Zhang, Q.; Jiang, Y.; Gou, B.-D.; Huang, J.; Gao, Y.-X.; Zhao, J.-T.; Zheng, L.; Zhao, Y.-D.; Zhang, T.-L.; Wang, K., In situ detection of calcium phosphate clusters in solution and wet amorphous phase by synchrotron X-ray absorption near-edge spectroscopy at calcium K-edge. Cryst. Growth Des. 2015,15 (5), 2204-2210.
2. Zhang, Z.-L.; Chen, X.-R.; Bian, S.; Huang, J.; Zhang, T.-L.; Wang, K., Identification of dicalcium phosphate dihydrate deposited during osteoblast mineralization in vitro. J. Inorg. Biochem. 2014,131 (0), 109-114.
3. Du, L.; Bian, S.; Gou, B.-D.; Jiang, Y.; Huang, J.; Gao, Y.-X.; Zhao, Y.-D.; Wen, W.; Zhang, T.-L.; Wang, K., Structure of clusters and formation of amorphous calcium phosphate and hydroxyapatite: From the perspective of coordination chemistry. Cryst. Growth Des. 2013,13 (7), 3103-3109.
4. Zhao, W.-H.; Gou, B.-D.; Zhang, T.-L.; Wang, K., Lanthanum chloride bidirectionally influences calcification in bovine vascular smooth muscle cells. J. Cell. Biochem. 2012,113 (5), 1776-1786.
5. Bian, S.; Du, L.-W.; Gao, Y.-X.; Huang, J.; Gou, B.-D.; Li, X.; Liu, Y.; Zhang, T.-L.; Wang, K., Crystallization in aggregates of calcium phosphate nanocrystals: A logistic model for kinetics of fractal structure development. Cryst. Growth Des. 2012,12 (7), 3481-3488.
6. Wang, C.-G.; Liao, J.-W.; Gou, B.-D.; Huang, J.; Tang, R.-K.; Tao, J.-H.; Zhang, T.-L.; Wang, K., Crystallization at multiple sites inside particles of amorphous calcium phosphate. Cryst. Growth Des. 2009,9 (6), 2620-2626.
7. Shi, Y.-L.; Wang, L.-W.; Huang, J.; Gou, B.-D.; Zhang, T.-L.; Wang, K., Lanthanum suppresses osteoblastic differentiation via pertussis toxin-sensitive G protein signaling in rat vascular smooth muscle cells. J. Cell. Biochem. 2009,108, 1184-1091.
8. Wang, C.; Zhang, Q.; Gou, B.-D.; Zhang, T.-L.; Wang, K., Differentiation-stimulating potency of differentiated HL60 cells after drug treatment. Biomed. Pharmacother. 2014, 68 (5), 581-588.
9. Wang, L. W.; Shi, Y. L.; Wang, N.; Gou, B. D.; Zhang, T. L.; Wang, K., Association of oxidative stress with realgar-induced differentiation in human leukemia HL-60 cells. Chemotherapy 2009, 55 (6), 460-467.
10. Wang, N.; Wang, L.-W.; Gou, B.-D.; Zhang, T.-L.; Wang, K., Realgar-induced differentiation is associated with MAPK pathways in HL-60 cells. Cell Biol. Intl. 2008, 32, 1497-1505.
11. Luo, L.-Y.; Huang, J.; Gou, B.-D.; Zhang, T.-L.; Wang, K., Induction of human promyelocytic leukemia HL-60 cell differentiation into monocytes by arsenic sulphide: Involvement of serine/threonine protein phosphatases. Leuk. Res. 2006, 30, 1399-1405.
12. Gou, B.-D.; Liu, Y.; Gao, Y.-X.; Tang, K.; Zheng, L.; Zhao, Y.-D.; Zhang, T.-L.*, Ex vivo detection of calcium phosphate and calcium carbonate in rat blood serum. J. Struct. Biol. 2019, 205 (1), 41-47.
13. Fan, H.-X.; Gou, B.-D.; Gao, Y.-X.; Wu, G.; Zhang, T.-L.*, Pseudo-equilibrium equation of calcium phosphate precipitation from aqueous solution. Phys. Chem. Chem. Phys. 2019, 21 (39), 22057-22066.
14. Zhang, Q.; Liu, Y.; Gou, B.-D.; Zheng, L.; Gao, Y.-X.; Zhang, T.-L.*, Quantitative chemical relations at pseudo-equilibrium in amorphous calcium phosphate formation. RSC Advances 2016, 6 (104), 102710-102723.
