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2017

1. Chao Tian, Meng Wang, Zifei Han, Fang Fang, Zhili Zhang, Xiaowei Wang, Junyi Liu. Design, synthesis and biological evaluation of novel 6-substituted pyrrolo [3,2-d] pyrimidine analogues as antifolate antitumor agents. European Journal of Medicinal Chemistry. 2017, 138, 630-643.

2. Meng Wang, Jiajia Yang, Mengmeng Yuan, Liangmin Xue, Hao Li, Chao Tian, Xiaowei Wang, Junyi Liu*, Zhili Zhang*. Synthesis and antiproliferative activity of a series of novel 6-substituted pyrido[3,2-d]pyrimidines as potential nonclassical lipophilic antifolates targeting dihydrofolate reductase. European Journal of Medicinal Chemistry. 2017, 128, 88-97.

3. Yixing Sun, Weisi Xu, Ningning Fan, Xuefeng Sun , Xianling Ning , Liying Mab, Junyi Liu *, Xiaowei Wang*. Design, synthesis and biological evaluation of (E)-3,4-dihydroxystyryl 4-acylaminophenethyl sulfone, sulfoxide derivatives as dual inhibitorsof HIV-1 CCR5 and integrase. Bioorganic & Medicinal Chemistry. 25 (2017) 1076–1084.

4. Yu Q, Zhang Z, Sun J, Xia Y, Du Q*, Liang D*. Effects of chain length and hydrophobicity/charge ratio of AMP on its antimicrobial activity. SCIENCE CHINA Chemistry. 2017. 10.1007/s11426-016-0415-6, 2017.

5. Zheng T, Hou Y, Zhang P, Zhang Z, Xu Y, Zhang L, Niu L, Yang Y, Liang D, Yi F, Peng W, Feng W, Yang Y, Chen J, Zhu YY, Zhang LH, Du Q*. Profiling single-guide RNA specificity reveals a mismatch sensitive core sequence. Scientific Reports. 7: 40638, 2017.

6. Liang D, Wang H, Song W, Xiong X, Zhang X, Hu Z, Guo H, Yang Z, Zhai S, Zhang LH, Ye M*, Du Q*. The decreased N6-methyladenine DNA modification in cancer cells. Biochemical and Biophysical Research Communications. 480(1):120-125, 2016.

7. Huang Y, Cheng Q, Jin X, Ji J, Guo S, Zheng S, Wang X, Cao H, Gao S, Liang X, Du Q, Liang Z. Systemic and tumor-targeted delivery of siRNA by cyclic NGR and isoDGR motif-containing peptides. Biomaterials Science. 4, 494-510, 2016.

8. Li-Qiang Han, Xia Yuan, Xing-Yu Wu, Ri-Dong Li, Bo Xu, Qing Cheng, Zhen-Ming Liu, Tian-Yan Zhou, Hao-Yun An, Xin Wang; Tie-Ming Cheng, Ze-Mei Ge, Jing-Rong Cui, Run-Tao Li      Urea-containing peptide boronic acids as potent proteasome inhibitors. European Journal of Medicinal Chemistry. (2017), 125, 925-939.

9. Songwen Lin, Yingbo Li, Yufen Zheng, Laichun Luo, Qi Sun, Zemei Ge, Tieming Cheng, Runtao Li. Design, synthesis and biological evaluation of quinazoline-phosphoramidate mustard conjugates as anticancer drugs.. European Journal of Medicinal Chemistry. (2017), 127, 442-458.

10. Liqiang Han, Yanzhao Wen, Ridong Li, Bo Xu, Zemei Ge, Xin Wang, Tieming Cheng, Jingrong Cui, Runtao Li. Synthesis and biological activity of peptide proline-boronic acids as proteasome inhibitors. Bioorganic & Medicinal Chemistry. (2017), 25(15), 4031-4044.

11. Wei Huang, Xia Yuan, Ting Sun, Shujie Fan, Jun Wang, Quan Zhou, Wei Guo, Fuxiang Ran, Zemei Ge, Huayu Yang, Runtao Li and Jingrong Cui. Proteasome Inhibitor YSY01A Abrogates Constitutive STAT3 Signaling via Down-regulation of Gp130 and JAK2 in Human A549 Lung Cancer Cells. Frontiers in pharmacology. (2017), 8, 476.

12. Li, Runrun; Wei, Qiang; Wang, Xin; Ge, Zemei; Li, Runtao. An Efficient Cascade Synthesis of Ethyl 3-Amino-5-oxoisoxazolidine-4-carboxylate Derivatives. Synthesis. (2017), 49, 4341-4349.

13. Hua, Yong; Zhang, Wenjie; Wang, Xin; Ge, Zemei; Li, Runtao. Synthesis of novel five-membered endocyclic sulfoximines -1-aryl-3-(arylimino)-3,5-dihydro- 1,4,2-dithiazole 1-oxides. Tetrahedron. (2017), 73(30), 4387-4391.

14. Du, Xiaolei; Yin, Dawei; Ge, Zemei; Wang, Xin; Li, Runtao. Asymmetric Michael addition reactions of pyrrolones with chalcones catalyzed by vicinal primary-diamine salts. RSC Advances. (2017), 7, 24547.

15. Xiaorong Zhang, Aqin Liu, Zhihui Zhao, Zhongjun Li*, Qing Li*. Synthesis of a series of new glycoclusters and the evaluation of their anti-adhesion activities. Carbohydr. Res. 2017, 450, 49-53.

16. Meng Sha, Wang Yao, Xiao Zhang, Zhongjun Li*. Synthesis of structure-defined branched hyaluronan tetrasaccharide glycoclusters. Tetrahedron Lett. 2017, 58, 2910-2914.

17. Meng-jie Xia, Wang Yao, Xiang-Bao Meng Zhongjun Li*. Co2(CO)6 -propargyl cation mediates glycosylation reaction by using thioglycoside. Tetrahedron Lett. 2017, 58, 2389-2392.

18. Yanhui Wang, Xiaoke Zhao, Qiuyun Kong, Jiajian Yao, Xiangbao Meng, Zhongjun Li*. Assembly of a β-(1 -3)-glucan laminari hexaose on ionic liquid support. Tetrahedron Lett. 2017, 58, 1655-1658.

19. Yunhe Wang, Shuai Meng, Tingting Yue, Chuchun Li*, Zhongjun Li*.  The rapid assembling of oligosaccharides by the developed HASP strategy. Chin. Chem. Lett. 2017, DOI: 10.1016/j.cclet.2017.09.045.

20. Xiao Zhang, Wang Yao, Xiaojiang Xu, Huifang Sun, Jinhua Zhao, Xiangbao Meng, Mingyi Wu, Zhongjun Li*. Synthesis of fucosylated chondroitin sulfate glycoclusters: a robust route to novel anticoagulant agents.  Chem. Eur. J. 2017, DOI: 10.1002/chem.201705177

21. Wan Fu, Xue Li, Xiaopeng Lu, Ran Li, Nan Zhang, Shan Liu, Yue Wang, Ying Zhao*, Xiangbao Meng*, and Wei-Guo Zhu*. A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells. Cell Death & Disease. 2017, 8(10):e3086.

22. Liyan Ji, Simin Yang, Shasha Li, Shan Liu, Shunan Tang, Zhongqiu Liu, Xiangbao Meng*, and Siwang Yu*. A novel triazolonaphthalimide induces apoptosis and inhibits tumor growth by targeting DNA and DNA-associated processes. Oncotarget. 2017, 8, 37394-37408.

23. Liangkun Pan, Nan Hang, Chao Zhang, Yu Chen, Shuchun Li, Yang Sun*, Zhongjun Li, and Xiangbao Meng*. Synthesis and Biological Evaluation of Novel Benzimidazole Derivatives and Analogs Targeting the NLRP3 Inflammasome. Molecules. 2017, 22, 213

24. Wenxing Zou, Zongze Huang, Kang Jiang, You Wu, Yuqing Xue, Franck Suzenet*, Qi Sun*, and Gérald Guillaumet. Chelation-Assisted C-S Activation/ Cascade Heteroannulation of Pyridine-2-thione Derivatives in Pd-Catalyzed Cross-coupling Reaction with Alkynes. Tetrahedron. 2017,73,5485 - 5492

25. Ningning Fan, Shuang Zhang, Tao Sheng, Liang Zhao, Zhenming Liu, Junyi Liu,  Xiaowei Wang*. Docking field-based QSAR and pharmacophore studies on the substituted pyrimidine derivatives targeting HIV-1 reverse transcriptase. Chem Biol Drug Des. 2017, DOI: 10.1111/cbdd.13086

26. Caixia Yu, Jiao Gong, Fu-ling Yin, Jian Huang, Tian-lan Zhang, Kui Wang. Influences of LaCl3 on the mineral phase transformation during osteoblast mineralization in vitro.   JES. 2017:88-96

27. Niu X ,Yang J , Yang X. Synthesis and anti-diabetic activity of new N, N-dimethylphenylene diamine-derivatized nitrilotriacetic acid vanadyl complexes. J. Inorg. Biochem. 2017, DOI:10.1016/j.jinorgbio.2017.06.017

28. Lu J, Zhang H, Chen X, Zou Y, Li J, Wang L, Wu M, Zang J, Yu Y, Zhuang W, Xia Q*,Wang J*. A small molecule activator of SIRT3 promotes deacetylation and activation of manganese superoxide dismutase. Free Radic Biol Med. 2017 Jul 12;112:287-297.

29. Wang W, Zhao Z, Zhang Z, Zhang C, Xiao S, Ye X,Zhang L, Xia Q*, Zhou D*. Redirect Killer T Cells via Displaying Azido Sugar for Tethering Ligands. Chembiochem. 2017 Sep 1. doi: 10.1002/cbic.201700340.

30. Xiaoqing Zheng, Wei Xu, Ruoxuan Sun, Hanwei Yin, Chaoran Dong, Huihui Zeng. Synergism between thioredoxin reductase inhibitor ethaselen and sodium selenite in inhibiting proliferation and inducing death of human non-small cell lung cancer cells. Chemico-Biological Interactions. 25275):74-85,2017

31. Xiaoqing Zheng, Weiwei Ma, Ruoxuan Sun, Hanwei Yin, Fei Lin, Yuxi LiuWei Xue, Huihui Zeng. Butaselen prevents hepatocarcinogenesis and rogression through inhibiting thioredoxin reductase activity. Redox Biology. 14 (2018) 237–249

32. Suofu Ye, Jian Li, Wei Lu, Huihui Zeng. Dose-biomarker-response modeling of the anticancer effect of Ethaselen in a human non-small cell lung cancer xenograft mouse model. Acta Pharmacologica. Sinica. 38(2):223-232, 2017 Feb

33. Ruijun Wu, Kai Zhu, Xiaodan Zhang, Sufang Zhang, Yanmeng Liu, Jinyu Ren, Cong Li, Min Ye, and Xiaomei Ling*. Nonimmobilized Biomaterial Capillary Electrophoresis for Screening Drugs Targeting Human Glucose Transporter 1. Analytical Chemistry. DOI: 10.1021/acs.analchem.7b03811

34. Weiwei Lin, Jianmei Zhang, Yanmeng Liu, Ruijun Wu, Haisong Yang, Xiaobo Hu, Xiaomei Ling*. Studies on diagnostic biomarkers and therapeutic mechanism of Alzheimer’s disease through metabolomics and hippocampal proteomics. European Journal of Pharmaceutical Sciences. 2017(105): 119–126

35. Yujie Shi*, Zujin Shi, Suxin Li, Yuan Zhang, Bing He, Dong Peng, Jie Tian, Ming Zhao, Xueqing Wang, Qiang Zhang. The interactions of single-wall carbon nanohorns with polar epithelium   . International Journal of Nanomedicine. 2017, 12: 4177-4194.

36. Zhi-Wei Yang, Feng Xu,*, Xin Liuc, Yi Cao, Qi Tanga, Qian-Yu Chena, Ming-Ying Shang, Guang-Xue Liu, Xuan Wang,* Shao-Qing Cai. An untargeted metabolomics approach to determine component differences and variation in their in vivo distribution between Kuqin and Ziqin, two commercial specifications of Scutellaria. RSC Advances. 20177, 54682–54695